One direct approach, known as the Fischer esterification reaction, involves the acid-catalyzed condensation of an alcohol and a carboxylic acid, yielding an ester and water. Aromatherapy has the potential of making the dreadful experience of chemotherapy more tolerable to the increasingly larger number of cancer patients globally. To ensure the reaction is complete an acid catalyst is commonly used. The present experiment will be the synthesis of a familiar organic compound called aspirin. Fats and oils are another type of natural ester; they are actually mixtures of glycerol triesters, made of long-chain fatty acids and glycerol glycerin: 1,2,3-propanetriol.
Yard 55 chem 3341-111 The Preparation of Aspirin The purpose of this experiment is to synthesize aspirin acetyl salicylic acid from salicylic acid and acetic anhydride. The process of synthesizing aspirin is an esterification reaction, meaning that the phenol group of the salicylic acid reacts with an acid anhydride, the functional group of acetic anhydride, to make ester. Stathopulos Department of Sciences, Chemistry Faculty University of Waterloo Teaching Assistant: Aaron Chan Prepared by: Section 001 Vithurjan Satkunarasan 20495383 Lab Partner: Ken Xu Introduction The synthesis of Acetaminophen is based on the amine group of p-aminophenol being acetylated by acetic anhydride to form an amide functional group. Acetic acid, Chemistry, Distillation 612 Words 3 Pages. According to Escobel, 2011 , Aspirin is synthesized through the reaction of salicylic acid with acetyl anhydride that causes a chemical reaction that turns salicylic acid's hydroxyl group. Atom, Chemical bond, Electric charge 879 Words 3 Pages Synthesis of Aspirin from Oil of Wintergreen Objectives: In this experiment, the Oil of Wintergreen is put into an Erlenmeyer flask containing sodium hydroxide to create sodium salicylate. When a compound on one side of the reaction is removed, equilibrium will shift towards the side it was removed from.
Filtration is used separate the impurities from the crude aspirin. . This produced the desired ester and water. The last step is the distillation. It is amazing already the breakthroughs that have surfaced within the past six years concerning. This concept is used throughout the lab when we are analyzing. Acetic acid, Acetic anhydride, Acid 2090 Words 7 Pages Synthesis of Aspirin Learning Goals 1.
Sulphuric acid, anti-bumping granules, rotary evaporator. Aspirin is synthesized from salicylic acid and acetic anhydride. I believe this question deserves to be further investigated; it may have the potential to help make chemotherapy more bearable by working with the medicine to increase the efficiency of chemotherapy. Figure1 is drawn using Chem Sketch software. After the ring stand was set up, a heating mantle was placed underneath the round-bottom flask and two rubber hoses were attached to the condensing tube. Acetic acid, Acetic anhydride, Aspirin 1897 Words 8 Pages Name Period Date The Synthesis of Aspirin Background Pharmaceutical research labs perform chemical reactions between organic molecules that contain mostly carbon.
The percent yield is calculated to determine the effectiveness of the reaction in preparing the desired product aspirin. If radio frequency waves of the appropriate energy are supplied, nuclei aligned with this field can absorb this radiation and reverse their spin and now oppose the applied magnetic field. This distillation will significantly purify the material, but not if there is alcohol or water present. To make sure the lab was done with the greatest amount of safety, all participants wore eye protection, tied up any lose clothing, tied long hair back and maintained a safe, well behaved manner. It is most commonly found in bananas but also can be found in other organisms. The boiling point of the final product at 121.
© 2009—2019 Adam Cap riola. Through this project, I discovered the possibility of using aromatherapy in chemotherapy. Acetic acid, Acetic anhydride, Acetyl 1799 Words 6 Pages future. Amides are the least reactive of the neutral carboxylic acid derivatives. The sulfuric acid catalyzed reaction of isopentyl alcohol with acetic acid to form isopentyl acetate is performed. Acetic anhydride and salicylic acid are mixed together, and then acidified by the addition of a few drops of concentrated sulfuric acid, which catalyzed the reaction. This quantitative error was most likely due to product getting stuck in the apparatus.
This small number of elements can be bonded together in different quantities, bonding types single, double, triple bonds , and structural. The thermometer is placed in the distillation head. The boiling point of the final product at 121. Acetic acid, Acetic anhydride, Aspirin 648 Words 2 Pages to synthesise pure aspirin using chemical tests such as esterification and recrystallization independently and to also find out the melting point range of aspirin using melting point determination. Second, if the temperature was too high in heating the mixture,.
The reaction components are added as follows. In organic chemistry, the reaction in which water molecule is released is known as condensation reaction Hornback, 2006. Aspirin, Chemistry, Distillation 1433 Words 5 Pages Preparation and melting point of Aspirin Aspirin is a painkilling drug and is produced worldwide to reduce and stop pain. Since the atoms in organic molecules tend to be nonmetals, then the bonds that hold them together are covalent bonds. Aim To determine the percentage of aspirin in different commercial preparations and to find which is the best value for money 2. It was found that 0.
The purpose of this experiment, is essentially to determine the purity of the product that is collected and filtered and recrystallized. In order to accomplish the reaction, the reactants were refluxed for an hour to yield the product. Acetic acid, Acetic anhydride, Aspirin 1206 Words 5 Pages purest aspirin when synthesized with salicylic acid and acetic anhydride to produce aspirin and acetic acid? The mechanism of the reaction involves initial protonation of the carboxyl group, attack by the nucleophilic hydroxyl, a proton transfer, and loss of water followed by loss of the catalyzing. This means that it is in fact possible to create artificial scents that could possibly have therapeutic properties. In the 19th century, a German chemist by the name of Felix Hoffman wanted to find a medication that would ease.